Kinetic River Awarded NCI Contract for Modular Flow Cytometer

Written by Sean Murphy. Posted in Clients in the News, skmurphy

Kinetic River Corp. has been awarded contract from the National Cancer Institute for a modular flow cytometer that will be used to test novel laser sources for applicability to flow cytometry. It will also serve as a test bed for new detectors, electronics and other technologies critical to the future of flow cytometry.

Kinetic River Corp. Awarded Contract from National Cancer Institute for Potomac Modular Flow Cytometer

The following is from a press release dated published today in PR Newswire. I have added hyperlinks not in the original to provide additional context.

Kinetic River Corp., a leader in flow cytometry instrumentation, announced today being awarded a contract from the National Cancer Institute (NCI) for delivery of its flagship Potomac modular flow cytometer, customized for the use of novel light sources.

The Potomac modular flow cytometer is a flexible platform designed for ease of modification and upgrades. Customizable from 1 to 7 lasers and from 4 to 20 detection channels, it can accommodate novel light sources and detectors.The Potomac modular flow cytometer is a flexible platform designed for ease of modification and upgrades. Customizable from 1 to 7 lasers and from 4 to 20 detection channels, it can accommodate novel light sources and detectors.

The Potomac is a flow cytometer designed for flexibility and modularity. Built almost entirely with off-the-shelf parts, it is easily customized and reconfigured. The Potomac fits the needs of customers unsatisfied with cookie-cutter flow cytometry solutions.

“The NCI order is a validation of our approach to instrument design and customization,” stated Giacomo Vacca, Ph.D., president of Kinetic River. “The needs of this customer simply could not be met with standard products. The Potomac’s open layout and modular architecture make it easy to integrate novel light sources and detectors, and to modify the system configuration over time.”

The Potomac flow cytometer was purchased by the laboratory of William Telford, Ph.D., at the National Cancer Institute, where it will be used to test novel laser sources for applicability to flow cytometry. It will also serve as a test bed for new detectors, electronics and other technologies critical to the future of flow cytometry.

The Potomac customized for NCI incorporates a fiber-coupled 488-nm laser light source, two scattering detectors, and five channels for fluorescence detection. It additionally receives laser beams from external sources, such as pulsed and supercontinuum lasers, for novel excitation of cell samples. The optical bench is based on rails and cube/rod assemblies from Excelitas Technologies, simplifying alignment and allowing easy reconfiguration.

For optical system design, Kinetic River uses its own proprietary modeling tools, which allow interactive design exploration on an intuitive dashboard interface. For customization of the instrument, it relies on BeamWise®, a 3D CAD optomechanical design tool that streamlines system development through the creation of a virtual optical bench.

About Kinetic River

Kinetic River Corp. is a biophotonics design and product development company specializing in life science research and biomedical applications. Based in California’s Silicon Valley, Kinetic River offers cutting-edge flow cytometry instrumentation solutions, including the Potomac and the Danube, a fluorescence lifetime flow cytometer. Kinetic River also provides a range of technical consulting services and training seminars to clients worldwide.

Potomac Originally Demonstrated at Photonics West 2015

The Potomac was developed by Dr. Giacomo Vacca in collaboration with Excelitas Technologies (the supplier of 97% of the optical and optomechanical components in the system). In this “making of” video Dr. Vacca explains how he designed and built a modular flow cytometer using off the shelf parts from the Excelitas product catalog. This flow cytometer was first demonstrated in operation at Photonics West 2015 in the Excelitas booth.

The Potomac modular flow cytometer was designed to support research use only applications on the cutting edge where exotic light sources, custom flow cells, or novel detection schemes may require flexibility and customization not available in fixed-layout off the shelf flow cytometers.

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To view the original version on PR Newswire, visit: http://www.prnewswire.com/news-releases/kinetic-river-corp-awarded-contract-from-national-cancer-institute-for-potomac-modular-flow-cytometer-300339661.html

Credits and Trademarks

  • Photo Credit: Kinetic River
  • Kinetic River® and the Kinetic River logo are registered trademarks of Kinetic River Corp.
  • BeamWise® is a registered trademark of BeamWise, Inc.

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